What’s EPM301? Is it More Potent than CBD, THC?

New evidence has emerged that cannabidiolic acid (CBDA), a natural chemical compound found in cannabis plants of which cannabinoids, like CBD and THC, are mere derivatives, can be far more potent than the cannabinoids themselves.


It’s true since it was none other than the “father of cannabis research”, Dr. Raphael Mechoulam, who revealed this in his latest discovery a few months ago.

The professor of Medicinal Chemistry at the Hebrew University of Jerusalem led the team of scientists at EPM, a US-based global biotechnology company (that he co-founded) to develop a synthetic, acid-based cannabinoid compound. According to Dr. Mechoulam, this synthetic compound is not only stable but can potentially be far more effective than CBD or THC, that too, with no adverse effects.

Named “cannabidiolic acid methyl ester” (or EPM301), this newly patented compound has kicked up quite a storm in the cannabis industry and generated a ripple effect on the future of medicine as well.

So far, owing to its highly unstable nature, cannabidiolic acid had been kept outside the purview of the pharmaceutical industry, despite its potential. This acid, found only in the living cannabis plants, is apparently rather difficult to isolate and preserve. With this latest discovery, however, the possibilities of utilizing this plant-based acid in the mainstream drug industry seem more and more likely!


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