Rats with regular access to cannabis seek more of the substance and tend to show increased drug-seeking behavior when cannabis is absent.
That’s according to a new study conducted by neuroscientists in Washington State University’s Integrative Physiology and Neuroscience unit.
The research, published in The Journal of Neuroscience, is the next step to better understand the cognitive and neural effects of cannabis use in humans.
“It’s always difficult to establish reliable cannabis-seeking behavior using animal models. In this study we have a clear and reliable response for cannabis by utilizing the very first self-administration model involving on-demand delivery of whole-plant cannabis vapor,” said Ryan McLaughlin, professor in WSU’s Integrative Physiology and Neuroscience unit.
So, how do you give a rat the option to self-administer cannabis?